On April 29th, LEoPARD’s research students Jack Macdonald and Sebastian Simonson attended the 2023 Saint Michael’s College Academic Symposium — and presented a poster entitled “Modulation of alkaline phosphatase activity by vanilloids: a quantitative structure-activity relationship (QSAR) study.” The poster represented a portion of the undergraduate research in which Macdonald and Simonson have been engaged since joining LEoPARD in the Fall 2022 semester. At the symposium — alongside many other students from various majors across campus — Macdonald and Simonson presented their work to a range of attendees, and answered rigorous questions.

Jack Macdonald and Sebastian Simonson present their undergraduate research poster, “Modulation of alkaline phosphatase activity by vanilloids: a quantitative structure-activity relationship (QSAR) study.”

Jack Macdonald and Sebastian Simonson present their work to Dr. Alain Brizard, Professor of Physics.

Jack Macdonald and Sebastian Simonson present their work to Dr. Bret Findley, Associate Professor of Chemistry, and other undergraduate onlookers.

Macdonald (Baraboo, WI) and Simonson (Spruce Grove, AB, Canada) are both second-year students (sophomores) majoring in Biochemistry. Both joined LEoPARD in the Fall 2022 semester, and are working in LEoPARD’s interventive arm — which focuses on development of novel insulin sensitizers and other therapeutic measures to reverse existing insulin resistance. Jack will be continuing his research over summer, funded by a Trustee Scholar summer fellowship, and both he and Sebastian are expected to be further continuing their work in the Fall semester.

Congratulations to both Jack and Sebastian, and many thanks for your hard work!

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Laboratory for Evaluation of Pharmacological Agents in Remediation of Disease (LEoPARD) is a biochemistry-focused undergraduate research group at Saint Michael’s College in Colchester, VT (Burlington metro area). We offer transformative, real-world laboratory experiences to ensure that our hard-working students evolve into our successful alumni! Interested students are invited to read about our research, and consider applying to be a member of our group.

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